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Dendritic filopodia
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Dendritic filopodia : ウィキペディア英語版
Dendritic filopodia
Dendritic filopodia are small, membranous protrusions found primarily on dendritic stretches of developing neurons. These structures may receive synaptic input, and can develop into dendritic spines. Dendritic filopodia are generally less-well studied than dendritic spines because their transient nature makes them difficult to detect with traditional microscopy techniques. Sample preparation can also destroy dendritic filopodia. However, it has been determined that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react to stimuli in different ways.〔Portera-Cailliau C, Pan DT, Yuste, R. 2003. Activity-Regulated Dynamic Behavior of Early Dendritic Protrusions: Evidence for Different Types of Dendritic Filopodia. ''J. Neurosci.'' 23(18):7129-7141〕
==Structure==
Dendritic filopodia are thin and hairlike. They are defined as having a length that is at least twice the width, and they do not display the bulbous head found on dendritic spines. Filopodia are devoid of most cellular organelles, and are composed primarily of actin cytoskeletal elements. Synaptic contacts may occur along the length of the filopodia, not only at the end.〔Fiala JC, Feinberg M, Popov V, Harris KM. 1998. Synaptogenesis via dendritic filopodia in developing hippocampal area CA1. ''J. Neurosci''.18(21):8900-11. PMID 9786995〕

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